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DOC News    July 1, 2004
Volume 1 Number 1 p. 14
© 2004 American Diabetes Association

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New Risk Factor for CVD in People with Diabetes

Researchers studying the link between diabetes and heart disease have foundanother indicator to help determine when a person with diabetes may bedeveloping cardiovascular disease. According to a recent study, high levels ofglycated LDL cholesterol represent a risk factor for the development ofatherosclerosis for people with diabetes.

The study, conducted by researchers at the Institute for Metabolic Researchat the University City Science Center in Philadelphia, found a positivecorrelation between glycated LDL and urinary albumin excretion, a knownpredictor for cardiovascular mortality. They also found a link betweenglycated LDL and elevated cholesterol and triglyceride concentrations, bothconsidered traditional indicators of an increased risk for cardiovasculardisease.

The researchers conclude that elevated levels of glycated LDL should beconsidered a risk factor for the development of atherosclerosis in people withdiabetes.

Coen MP, Jin Y, Lauenslager GT: Increased plasma glycatedlow-density lipoprotein concentrations in diabetes: A marker of atherogenicrisk, Diabetes Technology & Therapeutics 3: 348–356, 2004.


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