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DOC News    July 1, 2004
Volume 1 Number 1 p. 14
© 2004 American Diabetes Association

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High-Fiber Cereal and Postprandial Insulin

Recently reported research provides yet another reason for consuming high-fiber breakfast cereal. A group of investigators from the University of Toronto and St. Michael's Hospital—under funding from cereal maker General Mills—studied the effect of two ready-to-eat breakfast cereals on the plasma glucose and insulin responses on human volunteers.

One cereal, Fiber One, is considered a high-fiber choice, while Country Corn Flakes is a low-fiber cereal. The study included 78 nondiabetic men who consumed the cereal on two occasions following a 10- to 14-hour fast. Each volunteer consumed a test meal containing 25 mg of available carbohydrate. Blood was drawn at regular intervals for 2 hours following the meal.

Among all subjects, mean plasma glucose levels were significantly lower after the high-fiber meal at 15, 30, 45, and 60 minutes after eating, and higher than the low-fiber cereal at 90 and 120 minutes. Data from the 43 men with high fasting plasma insulin (FPI) on screening were compared to those from the 35 men with normal FPI. Analysis shows that plasma glucose response was significantly greater among hyperinsulinemic subjects at 60, 90, and 120 minutes, but not in control subjects.

"This study shows that a ready-to-eat breakfast cereal rich in cereal fiber elicited lower plasma glucose responses than a low-fiber cereal in both normal and hyperinsulinemic men but reduced postprandial insulin responses only in the hyperinsulinemic subjects," the authors observed. "This supports previous assertions that the relative glycemic effects of carbohydrate foods are the same in different subjects but suggests that the relative insulinemic effects of foods are not."

Wolever TM, Campbell JE, Geleva D, Anderson GH: High fiber cereal reduced postprandial insulin responses in hyperinsulinemic but not normoinsulinemic subjects. Diabetes Care 27: 1281–1285, 2004.[Abstract/Free Full Text]


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