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Erectile Dysfunction a Marker for CAD

Carmine Gazzaruso, MD, and colleagues at Maugeri Foundation Hospital in Pavia, Italy, evaluated the prevalence of ED in 133 men with uncomplicated diabetes who had angiographically verified silent CAD and in 127 diabetic men without evidence of myocardial ischemia.

Men with diabetes and silent CAD had nearly eight times the prevalence of ED of those without silent CAD (33.8% versus 4.7%). The authors evaluated several risk factors—including alipoprotein(a) polymorphism, smoking, microalbuminuria, HDL, and LDL—but none were as efficient a predictor of silent CAD as ED.

"If our findings are confirmed, ED may become a potential marker to identify diabetic patients to screen for silent CAD," the authors conclude.

Gazzuruso C, Giordanetti S, De Amici E, et al. Relationship between erectile dysfunction and silent myocardial ischemia in apparently uncomplicated type 2 diabetic patients. Circulation; published online June 21, 2004.

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