DOC News January 1, 2005
Volume 2 Number 1 p. 22
© 2005 American Diabetes Association
Metabolic Link Between Diabetes and MI
The global increase of type 2 diabetes is creating important cardiovascular
consequences worldwide because diabetes is a major risk factor for the
development of coronary artery disease. Approximately 20–30% of patients
who suffer an acute myocardial infarction (AMI) also have been previously
diagnosed with diabetes. These patients are at increased risk of both
short-term and long-term cardiovascular events in the future.
Researchers in the U.S., Canada, U.K., Argentina, and Russia collaborated
to study the risk associated with a new diagnosis of diabetes and outcome
after an AMI. David Aguilar, MD, and colleagues assessed the risk of death and
major cardiovascular events by studying 14,703 heart attack patients. These
patients were categorized as either previously diagnosed with diabetes before
the heart attack (23%); diagnosed with diabetes after the heart attack (4%);
or nondiabetic (73%).
Patients with newly diagnosed diabetes were younger and had fewer
complications than did patients with previously known diabetes. One year after
enrollment in the study, patients with previously known and newly diagnosed
diabetes showed a similar increase of adjusted risk of death and
cardiovascular events.
Aguilar D, Solomon SD, Kober L, et al.: Newly diagnosed and
previously known diabetes mellitus and 1-year outcomes of acute myocardial
infarction. Circulation 110:1572–1578, 2004.[Abstract/Free Full Text]
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