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DOC News    October 1, 2005
Volume 2 Number 10 p. 12
© 2005 American Diabetes Association

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Two Paths to Diabetes-Related CVD

Both obesity and physical activity are recognized risks for type 2 diabetes and its cardiovascular disease (CVD) fellow traveler, but does one carry more weight, so to speak, in the development of morbidity? According to an analysis of national data reported in the July issue of Diabetes Care, physical inactivity and obesity are independent risk factors for diabetes and related cardiovascular comorbidities.

Patrick W. Sullivan, PhD, of Colorado Health Sciences Center, and colleagues reviewed information from the Medical Expenditure Panel Survey (MEPS), a comprehensive survey of 68,500 adults conducted 2000–2002. MEPS collected detailed information about sociodemographic traits and health conditions, and physical characteristics such as height and weight.

Analysis revealed that the risk of developing diabetes and related CVD risk factors increased with body mass index (BMI) regardless of the level of physical activity. Those same risks also increased with physical inactivity regardless of BMI.

Compared with a normal-weight physically active adult, the risk of diabetes and related comorbidities was 1.5 times higher in a normal-weight inactive adult and 1.65 times higher in an overweight inactive adult. The risk of diabetes and hypertension was 1.7 times greater for a normal-weight inactive adult and 1.8 times greater for an overweight inactive adult, compared with a normal-weight physically active adult.

"Both physical activity and obesity seem to be strongly and independently associated with diabetes and diabetes-related comorbidities," the group concludes.

Sullivan PW, Morrato EH, Ghushchyan V, et al.: Obesity, inactivity, and the prevalence of diabetes and diabetes-related cardiovascular comorbidities in the U.S., 2000–2002. Diabetes Care 28:1599–1603, 2005.[Abstract/Free Full Text]


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