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CAD Linked to Impaired Glucose Tolerance

Recent research suggests that abnormal glucose tolerance is common inpeople with CAD without a previous diagnosis ofdiabetes.

A group of researchers studied glucose metabolism and insulin response in144 patients with CAD without a previous diagnosis of diabetes. Only 40% ofpatients had normal glucose tolerance, with 39% of patients considered to haveimpaired glucose tolerance and 21% found to have diabetes. Post-challengehyperinsulinemia was linked to the number of diseased coronary arteries and ahistory of myocardial infarction.

Satoh H, Terada H, Uehara A, et al.: Post-challengehyperinsulinaemia rather than hyperglycaemia is associated with the severityof coronary artery disease in patients without a previous diagnosis ofdiabetes mellitus. Heart 91:731–736, 2005.[Abstract/Free Full Text]

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