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DOC News    February 1, 2005
Volume 2 Number 2 p. 22
© 2005 American Diabetes Association

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Childhood Adiposity Predicts Adult Hypertrophy

Overweight during childhood is a predictor of left ventricular hypertrophy (LVH) in adulthood, according to an analysis of data from the Bogalusa Heart Study performed by a group of investigators at Tulane University Health Sciences Center in New Orleans.

LVH is known as a cardiovascular risk factor, but little was known about characteristics that might be noted earlier in life. Between 1973 and 1996, seven in-depth surveys of children between 4 and 17 years of age were conducted in the community of Bogalusa, La. LVM was determined by echocardiography on a sample of 467 young adults aged 20 to 38 years who participated in the study.

Researchers considered a number of factors, including race, sex, blood pressure, and blood cholesterol and lipid levels. Analysis of data revealed that body mass index (BMI) was a consistent predictor of LVH. Blood pressure also showed an effect, with LVH rising with increased systolic pressure, but to a less pronounced degree than BMI. It's possible, the authors conclude, that BMI and systolic hypertension may act in concert to result in LVH.

Li X, Li S, Ulusoy E, Chen W, Srinivasan SR, Berenson GS: Childhood adiposity as a predictor of cardiac mass in adulthood: the Bogalusa Heart Study. Circulation 110:3488–3492, 2004.[Abstract/Free Full Text]


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