DOC News February 1, 2005
Volume 2 Number 2 p. 22
© 2005 American Diabetes Association
Childhood Adiposity Predicts Adult Hypertrophy
Overweight during childhood is a predictor of left ventricular hypertrophy
(LVH) in adulthood, according to an analysis of data from the Bogalusa Heart
Study performed by a group of investigators at Tulane University Health
Sciences Center in New Orleans.
LVH is known as a cardiovascular risk factor, but little was known about
characteristics that might be noted earlier in life. Between 1973 and 1996,
seven in-depth surveys of children between 4 and 17 years of age were
conducted in the community of Bogalusa, La. LVM was determined by
echocardiography on a sample of 467 young adults aged 20 to 38 years who
participated in the study.
Researchers considered a number of factors, including race, sex, blood
pressure, and blood cholesterol and lipid levels. Analysis of data revealed
that body mass index (BMI) was a consistent predictor of LVH. Blood pressure
also showed an effect, with LVH rising with increased systolic pressure, but
to a less pronounced degree than BMI. It's possible, the authors conclude,
that BMI and systolic hypertension may act in concert to result in LVH.
Li X, Li S, Ulusoy E, Chen W, Srinivasan SR, Berenson GS:
Childhood adiposity as a predictor of cardiac mass in adulthood: the Bogalusa
Heart Study. Circulation 110:34883492, 2004.[Abstract/Free Full Text]

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