DOC News February 1, 2005
Volume 2 Number 2 p. 23
© 2005 American Diabetes Association
Low-Fat Diets and Hi-Mono Diets Studied
Considering the importance of weight loss for patients with type 2
diabetes, researchers at the Oregon Health and Science University studied the
effects of an ad lib low-fat, high-fiber diet versus a
high-monounsaturated-fat diet. Investigators sought to find the diet with the
greatest weight loss without increasing plasma lipids or lessening glycemic
control.
Eleven patients with type 2 diabetes were randomly assigned one of the
diets. Both diets had 125% of the estimated energy requirements to allow for
ad lib quantity self-selection. Over the next 6 weeks, researchers evaluated
body weight, fasting plasma lipid, lipoprotein, glucose, glycated hemoglobin
(A1C), fructosamine concentrations, insulin sensitivity, and glucose
disposal.
The low-fat, high-fiber diet significantly reduced body weight. Plasma
total and cholesterol concentrations tended to decrease with both diets. There
were no differences between the diet and the lipid profile response noted.
Plasma triacylglycerol concentrations, glycemic control, and insulin
sensitivity did not differ significantly between the two diets.
Contrary to expectations, "the ad lib, low-fat, high-fiber diet
promoted weight loss in type 2 diabetic patients without causing adverse
effects in plasma lipids or glycemic control," according to the authors.
Gerhard GT, Ahmann A, Meeuws K, et al.: Effects of a
low-fat diet compared with those of a high-monounsaturated fat diet on body
weight, plasma lipids and lipoproteins and glycemic control in type 2
diabetes. Am J Clin Nutr 80:668673, 2004.[Abstract/Free Full Text]

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