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DOC News    March 1, 2005
Volume 2 Number 3 p. 14
© 2005 American Diabetes Association

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Looking Beyond A1C Levels

Blood levels of glycated hemoglobin (A1C) are an important measure of diabetes care, indicating the quality of glucose control and the risk of microvascular complications. Despite its clinical value, however, A1C is not the best predictor of health care costs for people with type 2 diabetes, according to a group of University of California, San Diego, researchers and the HealthPartners Research Foundation in Bloomington, Minn.

Todd P. Gilmer, PhD, and colleagues thought variables such as A1C and the duration of diabetes would be strong predictors of health care costs. They aren't, according to the group's analysis reported in the January 2005 issue of Diabetes Care.

Investigators studied 1,694 adults with diabetes covered by Health Partners, a health plan with 600,000 members. Data were accumulated from a patient survey and medical-record review, merged with 3 years of medical claims. The analysis revealed that patients with coronary heart disease (CHD) and hypertension had 3-year costs 300% greater than those with diabetes alone. Patients with depression had a 50% increase in costs.

Hypertension, CHD, and depression are all stronger predictors of health care costs than A1C, according to the group. Higher A1C levels predicted higher costs only when the baseline level was >7.5%. Patients with A1C of 10% had costs 11% higher than those with A1C of 6%.

Along with keeping an eye on the clinically important A1C, greater efforts to manage or prevent CHD, hypertension, and depression are needed to control diabetes health care costs, the authors conclude.

Gilmer TP, O'Connor PJ, Rush WA, et al.: Predictors of health care costs in adults with diabetes. Diabetes Care 28:59–64, 2005.[Abstract/Free Full Text]


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