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DOC News    September 1, 2005
Volume 2 Number 9 p. 16
© 2005 American Diabetes Association

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Metabolic Syndrome and Heart Attack

Metabolic syndrome—a cluster of symptoms including hypertension,glucose intolerance, dyslipidemia, and a large waist size—is commonamong people who suffer acute myocardial infarction (AMI) and tends to beassociated with a worse outcome in the hospital, according to a recentreport.

Researchers studied metabolic syndrome in 633 consecutive patients treatedfor AMI. About 46% met the ATP III criteria for metabolic syndrome. Patientswith metabolic syndrome were older and more likely to be women than thosewithout the condition.

Data showed that metabolic syndrome was a strong predictor of severe heartfailure. When the group looked at individual components of metabolic syndrome,the link to severe heart failure was strongest for hyperglycemia, whichincreased the risk 3.3-fold.

"Metabolic syndrome appeared associated with worse in-hospitaloutcome, with a higher risk of development of severe heart failure,"researchers conclude.

Zeller M, Steg PG, Ravisy J, et al.: Prevalence and impactof metabolic syndrome on hospital outcomes in acute myocardial infarction.Arch Intern Med 165:1192–1198, 2005.[Abstract/Free Full Text]


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