DOC News October 1, 2006
Volume 3 Number 10 p. 12
© 2006 American Diabetes Association
Warnings of Macrovascular Disease in Women
Women with type 2 diabetes and microalbuminuria, but blood pressure within
a normal range, are more than three times more likely to suffer macrovascular
disease than men, according to a study reported in the August issue of
Diabetes Care.
Researchers conducted a followup study of 67 people with diabetes and
microalbuminuria who had been enrolled in a trial testing the short-term
effects of blood pressure drug therapy. None of the 46 men and 21 women had a
history of serious cardiovascular disease. They were followed for an average
of 4.7 years.
At the end of the follow-up period, eight of the women (38.1%) met the end
point of death, cardiovascular disease, cerebrovascular events, or peripheral
artery disease, compared with six of the men (13%). The risks for women were
3.19 times greater than for men when other risk factors were considered.
"[F]emale sex is an independent risk factor for macrovascular disease
and death in our study population," researchers conclude. "[O]ur
observations suggest that the cardiovascular risk of women with type 2
diabetes can be easily underestimated when additional risk factors are made
mandatory."
Zandbergen AA, Sijbrands EJ, Lamberts SW, et al.:
Normotensive women with type 2 diabetes and microalbuminuria are at high risk
for macrovascular disease. Diabetes Care 29: 1851–1855, 2006[Abstract/Free Full Text]
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