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DOC News    October 1, 2006
Volume 3 Number 10 p. 12
© 2006 American Diabetes Association

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Family Risks From Diabetes

First-degree relatives of people with diabetes are more likely to have impaired endothelial function and a concomitant impairment in the autonomic nervous system control of blood pressure, according to a recent report.

A group of investigators assessed 27 otherwise healthy children of a parent with diabetes. The evaluation included high-resolution ultrasound and other tests of vascular function. They were compared with 15 matched people with no link to diabetes.

Offspring of a parent with diabetes were more likely to have signs of impaired vascular function and a depressed baroreflex. Researchers suspect that the two effects are related.

Although a mechanism isn't understood, the authors suggest that patients whose parents have diabetes should be targeted for primary prevention, such as regular physical activity, to improve cardiovascular regulation.

Iellamo F, Tesauro M, Rizza S, et al.: Concomitant impairment in endothelial function and neural cardiovascular regulation in offspring of type 2 diabetic subjects. Hypertension 48: 418–423, 2006[Abstract/Free Full Text] .


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