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DOC News    March 1, 2006
Volume 3 Number 3 p. 19
© 2006 American Diabetes Association

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Relatives Benefit From Their Own Lifestyle Changes

Diet and healthful lifestyle changes can produce long-term beneficial effects in individuals closely related to people with diabetes, who have an increased risk of developing the disease.

Researchers studied the effect of dietary and lifestyle changes on 77 people, 25–55 years of age, who are first-degree relatives of people with diabetes. All the participants were healthy, without diabetes or glucose intolerance.

Participants were placed into three groups. One group was put on a diet aimed at reducing saturated fats, increasing monounsaturated fats from fish and vegetables, and increasing consumption of fresh fruits and vegetables. The diet also encouraged eating low–glycemic-index foods—which release glucose into the bloodstream slowly—and discouraged eating high–glycemic-index foods.

A second group was put on the diet and also encouraged to increase physical activity to a level of at least 30 minutes a day 4 or 5 days per week.

Members of the control group were told to keep to their usual diet and physical activity routines. At the end of 1 year, some of these participants were put on the same diet as the first group. All of the participants were followed for 2 years.

Analysis of data showed that dietary changes resulted in healthful benefits maintained for the entire 2-year study period. Participants in the second group also benefited from increased physical activity and lost an average 2.5% of their body weight. The improvements were greater among people who adopted diet and physical activity changes, compared with those who only followed the diet.

Brekke HK, Jansson P, Lenner RA: Long-term (1- and 2-year) effects of lifestyle intervention in type 2 diabetes relatives. Diabetes Res Clin Pract 70:225–234, 2005[Medline].


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