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Insulin Improves Coronary Artery Blood Flow

Investigators in Finland studied the effect of insulin on myocardial blood flow—as measured by single-photon emission-computed tomography (SPECT)—on 43 people with diabetes and CAD who were experiencing ischemia.

While patients were at rest, insulin increased myocardial blood flow by 13% in ischemic regions of the heart and 22% in nonischemic regions.

"In addition to its metabolic effects, insulin infusion may improve endovascular function and thus increase the threshold for ischemia and partly contribute to the beneficial effects found in clinical trials in these subjects," the researchers conclude.

Lautamaki R, Airaksinen KE, Seppanen M, et al.: Insulin improves myocardial blood flow in patients with type 2 diabetes and coronary artery disease. Diabetes 55:511–516, 2006[Abstract/Free Full Text] .

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This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Social Bookmarking                What's this?