DOC News August 1, 2006
Volume 3 Number 8 p. 12
© 2006 American Diabetes Association
BMI Raises Reflux Risk
Increasing body mass index (BMI) raises the risk of gastroesophageal reflux
in women, even among those in a normal weight range, according to a survey of
10,545 participants in the Nurses' Health Study.
Participants were asked about symptoms of gastroesophageal reflux, which
were compared with the results of BMI calculated when they enrolled in the
study. Researchers found a direct relationship between rising BMI and
gastroesophageal refluxas BMI increases, so do symptoms of reflux.
Women at the low end of normal BMI range were 30% less likely to have
gastroesophageal reflux, while those with a BMI
25 were twice as likely or
more to suffer the disorder.
Even within the normal weight ranges, an increase in BMI of
3.5 nearly
tripled the increased risk of gastroesophageal reflux. "Even moderate
weight gain among persons of normal weight may cause or exacerbate symptoms of
reflux," the researchers conclude.
Jacobson BC, Somers SC, Fuchs CS, et al.: Body-mass index
and symptoms of gastroesophageal reflux in women. N Engl J
Med 354:23402348, 2006[Abstract/Free Full Text]
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