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DOC News    October 1, 2007
Volume 4 Number 10 p. 5
© 2007 American Diabetes Association

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RESPONSE FROM DR. ECKEL:

Dr. Pokrywka appropriately points out the importance of reducing the circulating ApoB-containing lipoproteins to reduce the risk of cardiovascular disease, rather than raising HDL cholesterol.

I agree wholeheartedly that the evidence in patients with and without diabetes strongly supports LDL-lowering as the priority. HDL cholesterol and triglycerides remain at best second-class citizens until we know the benefit of favorably modifying their levels. My article simply reflected on strategies to increase HDL cholesterol if desired.


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