DOC News December 1, 2007
Volume 4 Number 12 p. 11
© 2007 American Diabetes Association
Lower Extremity Disease Provides Diabetes Diagnosis Tip-off
The prevalence of lower extremity diseases (LEDs) such as peripheral
neuropathy and peripheral arterial disease is nearly as high among people with
undiagnosed diabetes as among those with diagnosed cases, research indicates.
However, people with impaired fasting glucose—a marker of
pre-diabetes—had LED rates as low as those with normal glucose
levels.
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A group of investigators from the Centers for Disease Control and
Prevention analyzed data on 3,607 people ages
40 who participated in the
National Health and Nutrition Examination Survey (NHANES). Each participant
underwent testing to detect LEDs.
LEDs occurred most often in people with diabetes and least frequently in
people with normal blood glucose levels or impaired fasting glucose
(pre-diabetes). People with undiagnosed diabetes were about as likely to have
an LED as those diagnosed with the disease.
Researchers conclude that LEDs are common in people with diabetes,
including those with undiagnosed diabetes, but that rates are similarly low in
people with impaired fasting glucose or normal glucose levels. Results suggest
people with undiagnosed diabetes are a target population for LED detection,
they add.
Gregg EW, Gu Q, Williams D, et al.: Prevalence of lower
extremity diseases associated with normal glucose levels, impaired fasting
glucose, and diabetes among U.S. adults aged 40 or older. Diab Res
Clin Pract 77:485–488, 2007.[Medline]

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