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Obesity Contributes More to Diabetes Than Does Inactivity

Now a large-scale, long-term study of participants in the Nurses' Health Study adds an important piece of evidence. Researchers studied the incidence of diabetes among 69,000 women with no history of diabetes or cardiovascular disease. During 16 years of follow-up, 4,030 cases of diabetes were identified.

Analysis of collected data showed that the risk of diabetes rose with increased BMI and waist circumference and decreased levels of physical activity. But multivariate analysis revealed that obesity has a much more pronounced effect on diabetes risk than physical activity. Compared with a healthy, active woman of normal weight, an obese and inactive woman is nearly 17 times more likely to develop diabetes, while a woman who is obese but physically active is 10.74 times more likely to develop diabetes. A woman who is lean but inactive is about twice as likely to develop diabetes as a woman who is lean and active.

"The magnitude of risk contributed by obesity is much greater than that imparted by lack of physical activity," the researchers conclude.

Ana JS, Li TY, Manson JE, et al.: Adiposity compared to physical inactivity and risk of type 2 diabetes in women. Diabetes Care 30:53–58, 2007[Abstract/Free Full Text] .

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Services Email this article to a friend Similar articles in this journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Social Bookmarking                What's this?