DOC News April 1, 2007
Volume 4 Number 4 p. 11
© 2007 American Diabetes Association
Weight Loss and Glycemic Control
Losing weight can improve insulin action and glycemic control. But does it
make a difference whether weight is lost by reducing caloric intake or by
increasing energy expenditure?
Investigators studied the effects of caloric restriction and
exercise-induced energy expenditure on 36 sedentary men and women 50–60
years old with a body mass index of 23.5–29.9. Half the participants
were randomly assigned to one of two weight-loss strategies. One group was put
on an intervention that reduced caloric intake by 16% in the first 3 months
and 20% in the following 9 months. The remaining participants engaged in an
exercise program aimed at producing a similar energy deficit, increasing
energy expenditure by 16–20% over the 12-month study.
At the end of the study period, blood tests showed that both groups had
improvements in insulin activity and glycemic control. But one method of
weight loss did not produce changes significantly different from the
other.
Weiss EP, Racette SB, Villareal DT, et al.: Improvements in
glucose tolerance and insulin action induced by increasing energy expenditure
or decreasing energy intake: A randomized controlled trial. Am J
Clin Nutr 84:1033–1042, 2006[Abstract/Free Full Text]
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